Invitrogen™ RITA1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA558654

Catalog No. PIPA558654

Description

Immunogen sequence: AGPSKTEPGP AADSQKLSMG GLHSSRPLKR GLSHSLTHLN VPSTGHPATS APHTNGPQDL RPSTSGVTFR SPLVTSRARS VSISVPST Highest antigen sequence identity to the following orthologs: Mouse - 59%, Rat - 56%.

Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis.

Specifications

• Antigen: RITA1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RITA1
• Gene Alias: C12orf52; PSEC0043; RBPJ interacting and tubulin associated 1; RBPJ-interacting and tubulin-associated protein; RBPJ-interacting and tubulin-associated protein 1; RITA; RITA1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 84934
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q96K30
• Gene Symbols: RITA1
• Immunogen: Recombinant protein corresponding to Human RITA1. Recombinant protein control fragment (Product #RP-97761).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG