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Invitrogen™ RKHD4 Polyclonal Antibody
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Catalog No. PIPA520639
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100 μg
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Catalog No. Quantity
PIPA520639 100 μg
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Catalog No. PIPA520639 Supplier Invitrogen™ Supplier No. PA520639
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Rabbit Polyclonal Antibody

Suggested positive controls are mouse thymus or rat thymus tissue lysate. PA5-20639 can be used with blocking peptide PEP-0759.

Rkhd4, also known as MEX3A is a member of a novel family of four homologous human MEX3 proteins each containing two heterogeneous nuclear ribonucleoprotein K homology (KH) domains and one carboxy-terminal RING finger module. MEX3 proteins, including Rkhd4, are phosphoproteins that bind RNA through their KH domains and shuttle between the nucleus and the cytoplasm via the CRM1 export pathway. These proteins are a novel family of evolutionarily conserved RNA-binding proteins, differentially recruited to P bodies and potentially involved in post-transcriptional regulatory mechanisms. While Rkhd2 has been suggested to be associated with susceptibility to essential hypertension type 8, the function of Rkhd4 remains unknown. Rkhd3 and Rkhd4, but not Rkhd2, co-localize with both the hDcp1a decapping factor and Argonaute (Ago) proteins in processing bodies (P bodies), recently characterized as centers of mRNA turnover.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RKHD4
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene MEX3A
Gene Accession No. A1L020
Gene Alias 2700083E18Rik; Gm411; mex3 homolog A; mex3 homolog A (C. elegans); mex-3 RNA binding family member A; MEX3A; MEX-3A; RGD1564904; ring finger and KH domain containing 4; ring finger and KH domain containing protein; RING finger and KH domain-containing protein 4; RKHD4; RNA-binding protein MEX3A
Gene Symbols MEX3A
Host Species Rabbit
Immunogen A peptide corresponding to 14 amino acid synthetic peptide near the carboxy terminus of human RKHD4. The immunogen is located within amino acids 420-470 of RKHD4.
Purification Method Antigen Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 310631, 72640, 92312
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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