Invitrogen™ RM30 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA571152

Catalog No. PIPA571152

Description

This target displays homology in the following species: Dog: 80%; Human: 100%; Mouse: 91%; Rabbit: 89%; Rat: 91%.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Alternative splicing results in multiple transcript variants. Pseudogenes corresponding to this gene are found on chromosomes 6p and 12p. Read-through transcription also exists between this gene and the neighboring upstream lipoyltransferase 1 (LIPT1) gene.

Specifications

• Antigen: RM30
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MRPL30
• Gene Alias: 2310001L22Rik; 39S ribosomal protein L28, mitochondrial; 39S ribosomal protein L30, mitochondrial; HSPC249; L28mt; L30MT; Mitochondrial large ribosomal subunit protein uL30m; mitochondrial ribosomal protein L30; MRPL28; MRP-L28; MRPL28M; MRPL30; MRP-L30; RPML28
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51263
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q8TCC3
• Gene Symbols: MRPL30
• Immunogen: synthetic peptide directed towards the C-terminal region of human RM30.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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