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  5. Tocris Bioscience™ RN 1734

Tocris Bioscience™ RN 1734
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Catalog No. 374625
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25 mg
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Catalog No. Quantity
37-462-5 25 mg
37-465 5 mg
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Catalog No. 37-462-5 Supplier Tocris Bioscience™ Supplier No. 3746/25
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Description

Selective TRPV4 antagonist

RN 1734 is a selective TRPV4 antagonist (IC50 values are 2.3, 3.2 and 5.9 μM for hTRPV4, rTRPV4 and mTRPV4 receptors respectively). Displays selectivity for TRPV4 over other TRP channels (IC50 values are 2.3, >30, >30 and >100 μM for TRPV4, TRPV3, TRPM8 and TRPV1 respectively). Blocks TRPV4-mediated arteriole vasodilation and increases myogenic tone ex vivo.

Specifications

Chemical Name or Material 2,4-Dichloro-N-isopropyl-N-(2-isopropylaminoethyl)benzenesulfonamide
CAS 946387-07-1
Quantity 25 mg
Molecular Formula C14H22Cl2N2O2S
Formula Weight Observed MW: 353.31
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