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Invitrogen™ RNASE4 Polyclonal Antibody, Invitrogen™

Catalog No. PIPA5121641
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100 μL
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PIPA5121641 20 μL
PIPA5121640 100 μL
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Catalog No. PIPA5121641 Supplier Invitrogen™ Supplier No. PA5121641
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Rabbit Polyclonal Antibody

RNase 4 and RNase 5/ang 1 are unique among the RNase A ribonuclease genes in that they maintain a complex gene locus that is conserved across species with transcription initiated from tissue-specific dual promoters followed by differential exon splicing. Rnase4 (ribonuclease, RNase A family 4) gene can produce 2 transcripts both encoding 148 amino acid proteins. Rnase 4 is a member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. RNase 4 prefers poly(C) as a substrate and hydrolyzes 2',3'-cyclic nucleotides, with a pH optimum near 8.0. mRNA encoding RNase 4 is detectable in human pancreas, lung, skeletal muscle, heart, kidney and placenta; liver represents the most abundant source.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RNASE4
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
Gene RNASE4
Gene Accession No. O55004, P34096
Gene Alias C730049F20Rik; Rab1; Ribonuclease 4; ribonuclease A B1; ribonuclease A family member 4; ribonuclease, RNase A family 4; ribonuclease, RNase A family, 4; RL3; RNase 4; RNASE4; RNS4
Gene Symbols RNASE4
Host Species Rabbit
Immunogen Recombinant RNASE4 (Asp30-Gly147) expressed in E.coli.
Purification Method Protein A, Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56759, 6038
Target Species Human, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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