Invitrogen™ RNaseL Monoclonal Antibody (2E9)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA116575

Catalog No. AMPA6575

Description

This antibody does not react with mouse or rat samples.

A virally induced endoribonuclease, RNase L is the terminal factor of the anti-viral action of interferon. Activation of RNase L results in inhibition of viral proliferation. Activation of RNase L has also been determined to degrade RNA, thus, initiating a cellular stress response, inducing apoptosis. Since mutations in RNase L relate to an increased incidence of prostate cancer, the activation of RNase L functions in counteracting prostate cancer, via apoptosis.

Specifications

• Antigen: RNaseL
• Classification: Monoclonal
• Concentration: 1.0 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: Q05823
• Gene Symbols: RNASEL
• Immunogen: Purified, full-length, recombinant, human RNaseL produced in insect cells.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Monkey, Hamster
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Clone: 2E9
• Conjugate: Unconjugated
• Gene: RNASEL
• Gene Alias: 2',5'-oligoisoadenylate synthetase-dependent; 2-5A-dependent ribonuclease; 2-5A-dependent RNAase; 2-5A-dependent RNase; E230029I04Rik; I79_009550; interferon-induced 2-5A-dependent RNase; PRCA1; Ribonuclease 4; ribonuclease L; ribonuclease L (2 5-oligoisoadenylate synthetase-dependent); ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent); ribonuclease L (2, 5-oligoisoadenylate synthetase-dependent); ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent); RNase L; Rnasel; RNS4
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 100763013, 6041
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid