Invitrogen™ RNaseL Polyclonal Antibody

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
PIPA5119400	Invitrogen™ PA5119400	200 μL
PIPA5121637	Invitrogen™ PA5121637	20 μL

Description

RNaseL Polyclonal Antibody for Western Blot, ICC/IF, IHC (P)

A virally induced endoribonuclease, RNase L is the terminal factor of the anti-viral action of interferon. Activation of RNase L results in inhibition of viral proliferation. Activation of RNase L has also been determined to degrade RNA, thus, initiating a cellular stress response, inducing apoptosis. Since mutations in RNase L relate to an increased incidence of prostate cancer, the activation of RNase L functions in counteracting prostate cancer, via apoptosis.

Specifications

• Antigen: RNaseL
• Content And Storage: -20°C
• Classification: Polyclonal
• Form: Liquid
• Isotype: IgG
• Target Species: Human
• Gene: RNASEL
• Gene Alias: 2',5'-oligoisoadenylate synthetase-dependent; 2-5A-dependent ribonuclease; 2-5A-dependent RNAase; 2-5A-dependent RNase; E230029I04Rik; I79_009550; interferon-induced 2-5A-dependent RNase; PRCA1; Ribonuclease 4; ribonuclease L; ribonuclease L (2 5-oligoisoadenylate synthetase-dependent); ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent); ribonuclease L (2, 5-oligoisoadenylate synthetase-dependent); ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent); RNase L; Rnasel; RNS4
• Gene Symbols: RNASEL
• Primary or Secondary: Primary
• Purification Method: Antigen Affinity Chromatography

• Concentration: 0.68 mg/mL
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Conjugate: Unconjugated
• Host Species: Rabbit
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300
• Gene Accession No.: Q05823
• Gene ID (Entrez): 6041
• Immunogen: Recombinant protein Ribonuclease L. The antigen corresponds to amino acid range 358-583 of the target protein.
• Product Type: Antibody