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Invitrogen™ RNASET2 Polyclonal Antibody

Catalog No. PIPA532031
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100 μL
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Catalog No. Quantity
PIPA532031 100 μL
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Catalog No. PIPA532031 Supplier Invitrogen™ Supplier No. PA532031

Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, Jurkat, Raji. Predicted reactivity: Rhesus Monkey (95%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

RNASET2 is a novel member of the Rh/T2/S-glycoprotein class of extracellular ribonucleases. It is a single copy gene that maps to 6q27, a region associated with human malignancies and chromosomal rearrangement, and has been suggested to function as a tumor suppressor protein. Its expression is suppressed in Human T-cell Leukemia Virus type 1 (HTLV-1) infected cells following the binding of the HTLV-1 Tax protein to the RNASET2 promoter. As Adult T-cell leukemia (ATL) is one of the primary diseases caused by HTLV-1 infection, a reduction in the level of RNASET2 by Tax may play a role in ATL development.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RNASET2
Applications Western Blot
Classification Polyclonal
Concentration 0.81 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene RNASET2
Gene Accession No. O00584
Gene Alias 0610007O07Rik; 4833423A10Rik; 4930532K22Rik; bA514O12.3; C79750; Ribonuclease 6; Ribonuclease 6-A; Ribonuclease 6-B; Ribonuclease T2; ribonuclease T2A; Ribonuclease T2-A; Ribonuclease T2-B; RNase T2; RNASE6PL; RNASET2; Rnaset2a; Rnaset2b; rnt2; RP11-514O12.3
Gene Symbols RNASET2
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human Ribonuclease T2. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8635
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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