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Invitrogen™ RNASET2 Polyclonal Antibody
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Catalog No. PIPA584726
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100 μL
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PIPA584726 100 μL
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Catalog No. PIPA584726 Supplier Invitrogen™ Supplier No. PA584726
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LTKQDQQLQN CTEPGEQPSP KQEVWLANGA AESRGLRVCE DGPVFYP Highest antigen sequence indentity to the following orthologs: Mouse - 62%, Rat - 60%.

RNASET2 is a novel member of the Rh/T2/S-glycoprotein class of extracellular ribonucleases. It is a single copy gene that maps to 6q27, a region associated with human malignancies and chromosomal rearrangement, and has been suggested to function as a tumor suppressor protein. Its expression is suppressed in Human T-cell Leukemia Virus type 1 (HTLV-1) infected cells following the binding of the HTLV-1 Tax protein to the RNASET2 promoter. As Adult T-cell leukemia (ATL) is one of the primary diseases caused by HTLV-1 infection, a reduction in the level of RNASET2 by Tax may play a role in ATL development.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RNASET2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene RNASET2
Gene Accession No. O00584
Gene Alias 0610007O07Rik; 4833423A10Rik; 4930532K22Rik; bA514O12.3; C79750; Ribonuclease 6; Ribonuclease 6-A; Ribonuclease 6-B; Ribonuclease T2; ribonuclease T2A; Ribonuclease T2-A; Ribonuclease T2-B; RNase T2; RNASE6PL; RNASET2; Rnaset2a; Rnaset2b; rnt2; RP11-514O12.3
Gene Symbols RNASET2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human RNASET2. Recombinant protein control fragment (Product #RP-103844).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8635
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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