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Tocris Bioscience™ RNB 61
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10 mg
Description
RNB 61 is a highly potent and selective cannabinoid CB2 receptor (CB2R) agonist (Ki = 0.57 nM). RNB 61 shows >5000-fold selectivity for hCB2R over hCB1R. In vivo, RNB 61 inhibits the FSK-induced cAMP formation on mouse, rat, and dog CB2Rs (EC50 values ranging from 0.13 to 1.86 nM). RNB 61 has a a peripherally restricted action and exerts a nephroprotective and/or antifibrotic effects in animal models of kidney disease.
Specifications
Specifications
Chemical Name or Material | N-[(3E)-5-tert-Butyl-2-(cyclobutylmethyl)-1-methyl-1,2-dihydro-3H-pyrazol-3-ylidene]-2-(2-hydroxy-2-methylpropoxy)-5-(trifluoromethyl)benzamide |
CAS | 1217403-51-4 |
Quantity | 10 mg |
Target | Cannabinoid R2/CB2 Agonists |
Molecular Formula | C25H34F3N3O3 |
Purity | 0.97 |
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