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Invitrogen™ RND2 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA575726
Description
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
The Ras p21 family of guanine nucleotide proteins has been widely studied in view of its apparent role in signal transduction pathways and high frequency of mutations in human malignancies. It is now clear, however, that the Ras proteins (H-, K- and N-Ras p21) are members of a much larger superfamily of related proteins. Six members of this family, Rap 1A, Rap 1B, Rap 2, R-Ras, Ral A and Ral B, exhibit approximately 50% amino acid homology to Ras. The six mammalian Rho proteins (Rho A, B, C, G, 7 and 8) are approximately 30% homologous to Ras and are expressed in a wide range of cell types. Both Ras p21 and Rho p21, as well as other members of the Ras superfamily, contain a carboxy-terminal CAAX sequence (C, cysteine; A, aliphatic amino acid; X, any amino acid) which in the case of Ras has been shown to be essential for correct localization and function.
Specifications
RND2 | |
Polyclonal | |
Unconjugated | |
RND2 | |
aplysia ras-related homolog N (RhoN); ARHN; CTD-3199J23.4; GTP-binding protein Rho7; ras homolog gene family, member N; ras homolog N (RhoN); Rho family GTPase 2; RHO7; RhoN; Rho-related GTP-binding protein Rho7; rho-related GTP-binding protein RhoN; Rnd2; Rohn | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
11858, 303553, 8153 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Western Blot | |
1 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2 | |
P52198, Q9QYM5 | |
RND2 | |
Synthetic peptide corresponding to residues in Human RND2. | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
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