RND3 Mouse anti-Human, Clone:5C7B6, Abnova™

Catalog No.	Quantity
89-333-071	100 μg

Catalog No. 89-333-071 Supplier Abnova Corporation Supplier No. MAB16748

Description

Mouse monoclonal antibody raised against recombinant human RND3.

Members of the Rho family of Ras-related GTPases, such as ARHE, regulate the organization of the actin cytoskeleton in response to extracellular growth factors. Like Ras (MIM 190020), Rho family members appear to cycle between an inactive GDP-bound form and an active GTP-bound form. Three major regulators of Rho activity have been identified: RhoGDIs, which interact with the GDP-bound Rho proteins to keep them in a resting complex (see MIM 601925); GEFs, which promote GDP/GTP exchange leading to activation of Rho proteins (see MIM 601855); and GAPs, which stimulate GTP hydrolysis and return the activated Rho protein to its inactive form (see MIM 602680) (Nobes et al., 1998 [PubMed 9531558]).[supplied by OMIM]

Specifications

• Antigen: RND3
• Applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: 5C7B6
• Conjugate: Unconjugated
• Description: Rho family GTPase 3
• Dilution: ELISA (1:10000)
  Western Blot (1:500-1:2000)
  Immunohistochemistry (1:200-1:1000)
  Immunocytochemistry (1:200-1:1000)
  Flow Cytometry (1:200-1:400)
  The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.05% sodium azide)
• Gene: RND3
• Gene Alias: ARHE, Rho8, RhoE, memB
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to amino acid 104-241 of human RND3 from E. coli.
• Quantity: 100 μg
• Gene ID (Entrez): 390
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1