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Invitrogen™ RNF111 Polyclonal Antibody
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Catalog No. PIPA5106655
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100 μL
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PIPA5106655 100 μL
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Catalog No. PIPA5106655 Supplier Invitrogen™ Supplier No. PA5106655
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total RNF111.

The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012].
TRUSTED_SUSTAINABILITY

Specifications

Antigen RNF111
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene RNF111
Gene Accession No. Q6ZNA4, Q99ML9
Gene Alias ARK; Arkadia; E3 ubiquitin-protein ligase Arkadia; hRNF111; ring finger 111; RING finger protein 111; RING-type E3 ubiquitin transferase Arkadia; Rnf111
Gene Symbols RNF111
Host Species Rabbit
Immunogen A synthesized peptide derived from human RNF111(Accession Q6ZNA4), corresponding to amino acid residues Y907-R957.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 300813, 54778, 93836
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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