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RNF125 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501988940
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100 μL
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50-198-8940 100 μL
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Catalog No. 50-198-8940 Supplier Bioss Supplier No. BS9250R
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Rabbit Polyclonal Antibody

TRAC-1 is a 232 amino acid protein containing an N-terminal RING-type zinc finger domain. It functions as a positive regulator in the T-cell receptor signaling pathway, thus leading to T-cell activation. It mediates ubiquitination and subsequent proteasomal degradation of target proteins. TRAC-1 is expressed in lymphoid tissues, including bone marrow, spleen, thymus as well as in other tissues. It is predominantly expressed in the CD4+ and CD8+ T-cells, suggesting that it is preferentially confined to T-cells.

Specifications

Antigen RNF125
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene RNF125
Gene Accession No. Q96EQ8
Gene Alias 4930553F04Rik; E3 ubiquitin-protein ligase RNF125; RING finger protein 125; ring finger protein 125, E3 ubiquitin protein ligase; RNF125; T-cell RING activation protein 1; T-cell ring protein identified in activation screen; TNORS; TRAC1; TRAC-1
Gene Symbols RNF125
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human TRAC1/RNF125.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54941
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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