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Invitrogen™ RNF139 Polyclonal Antibody
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Catalog No. PIPA542295
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100 μL
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PIPA542295 100 μL
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Catalog No. PIPA542295 Supplier Invitrogen™ Supplier No. PA542295
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Description

Rabbit Polyclonal Antibody

Peptide sequence: SQRSLFKFYT YSSAFLLAAT SVLVNYYASL HIDFYGAYNT SAFGIELLPR Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 87%; Rat: 100%.

The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a ttranslocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RNF139
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene RNF139
Gene Accession No. Q8WU17
Gene Alias 4930555P18Rik; E3 ubiquitin-protein ligase RNF139; HRCA1; MGC31961; multiple membrane spanning receptor TRC8; patched related protein translocated in renal cancer; RCA1; RING finger protein 139; RING finger protein 139; E3 ubiquitin-protein ligase RNF139; RING-type E3 ubiquitin transferase RNF139; RNF139; translocation in renal carcinoma on chromosome 8 protein; TRC8
Gene Symbols RNF139
Host Species Rabbit
Immunogen Synthetic peptide directed towards the N-terminal of human RNF139 (aa 72-121).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11236
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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