Invitrogen™ RNF139 Polyclonal Antibody

Catalog No.	Quantity
PIPA518148	100 μg

Catalog No. PIPA518148 Supplier Invitrogen™ Supplier No. PA518148

Description

Goat Polyclonal Antibody

This antibody is predicted to react with canine based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 16,000.

The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a ttranslocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP.

Specifications

• Antigen: RNF139
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene: RNF139
• Gene Accession No.: Q8WU17
• Gene Alias: 4930555P18Rik; E3 ubiquitin-protein ligase RNF139; HRCA1; MGC31961; multiple membrane spanning receptor TRC8; patched related protein translocated in renal cancer; RCA1; RING finger protein 139; RING finger protein 139; E3 ubiquitin-protein ligase RNF139; RING-type E3 ubiquitin transferase RNF139; RNF139; translocation in renal carcinoma on chromosome 8 protein; TRC8
• Gene Symbols: RNF139
• Host Species: Goat
• Immunogen: Synthetic peptide sequence (HTGAAAEEFNDDT) corresponding to the C-terminus amino acids of RNF139 (aa 651-664).
• Purification Method: Ammonium sulfate precipitation
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 11236
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG