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  6. RNF144B/IBRDC2 Rabbit anti-Human, Polyclonal, Proteintech 

RNF144B/IBRDC2 Rabbit anti-Human, Polyclonal, Proteintech
SDP

Catalog No. 501735301 Shop All Proteintech Group Inc Products
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50-173-5301 150 μL
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Catalog No. 50-173-5301 Supplier Proteintech Group Inc Supplier No. 263061AP150UL
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Description

Rabbit Polyclonal Antibody

E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a p53/TP53-dependent but caspase-independent mechanism. However, its overexpression also produces a decrease of the ubiquitin-dependent stability of BAX, a pro-apoptotic protein, ultimately leading to protection of cell death; But, it is not an anti-apoptotic protein per se.

Specifications

Antigen RNF144B/IBRDC2
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene RNF144B
Gene Accession No. Q7Z419
Gene Alias IBRDC2, KIAA0161, p53RFP, ring finger protein 144B, RNF144B
Gene Symbols RNF144B
Host Species Rabbit
Immunogen RNF144B/IBRDC2 Fusion Protein Ag23679
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 255488
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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