RNF144B Mouse anti-Human, Clone: OTI7H2, liquid, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene TA500698

Catalog No. 50-167-1839

Description

E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a p53/TP53-dependent but caspase-independent mechanism. However, its overexpression also produces a decrease of the ubiquitin-dependent stability of BAX, a pro-apoptotic protein, ultimately leading to protection of cell death; But, it is not an anti-apoptotic protein per se.

Specifications

• Antigen: RNF144B
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q7Z419
• Gene Symbols: RNF144B
• Immunogen: Human recombit protein fragment corresponding to amino acids 1-256 of human RNF144B produced in E.coli
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence
• Clone: OTI7H2
• Conjugate: Unconjugated
• Gene: RNF144B
• Gene Alias: IBRDC2, PIR2, bA528A10.3, p53RFP
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 255488
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid