Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA589387

Invitrogen™ RNF144B Polyclonal Antibody
GREENER_CHOICE

Catalog No. PIPA589387
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA589387 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIPA589387 Supplier Invitrogen™ Supplier No. PA589387
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Immunogen sequence: MGSAGRLHYL AMTAENPTPG DLAPAPLITC KLCLCEQSLD KMTTLQECQC IFCTACLKQY MQLAIREGCG SPITCPDMVC LNHGTLQEAE IACLVPVDQF QLYQRLKFER EVHLDPYRTW CPVADCQTVC PVASSDPGQP VLVECPSCHL KFCSCCKDAW HAEVSCRDSQ PIVLPTEHRA LFGTDAEAPI KQCPVCRVYI; Positive Samples: Mouse kidney, Rat liver, ; Cellular Location: Cytoplasm, Mitochondrion membrane, Single-pass membrane protein.

E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a p53/TP53-dependent but caspase-independent mechanism. However, its overexpression also produces a decrease of the ubiquitin-dependent stability of BAX, a pro-apoptotic protein, ultimately leading to protection of cell death; But, it is not an anti-apoptotic protein per se.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RNF144B
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.87 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene RNF144B
Gene Accession No. Q8BKD6
Gene Alias bA528A10.3; BC025007; E130105P19Rik; E3 ubiquitin-protein ligase RNF144B; IBR domain containing 2; IBR domain-containing protein 2; IBRDC2; p53-inducible RING finger protein; p53RFP; PIR2; RING finger protein 144B; Rnf144b
Gene Symbols RNF144B
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human RNF144B (NP_8774342).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 218215, 364681
Target Species Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.