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Invitrogen™ RNF144B Polyclonal Antibody
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Catalog No. PIPA5106659
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100 μL
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PIPA5106659 100 μL
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Catalog No. PIPA5106659 Supplier Invitrogen™ Supplier No. PA5106659
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total RNF144B.

E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a p53/TP53-dependent but caspase-independent mechanism. However, its overexpression also produces a decrease of the ubiquitin-dependent stability of BAX, a pro-apoptotic protein, ultimately leading to protection of cell death; But, it is not an anti-apoptotic protein per se.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RNF144B
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene RNF144B
Gene Accession No. Q7Z419, Q8BKD6
Gene Alias bA528A10.3; BC025007; E130105P19Rik; E3 ubiquitin-protein ligase RNF144B; IBR domain containing 2; IBR domain-containing protein 2; IBRDC2; p53-inducible RING finger protein; p53RFP; PIR2; RING finger protein 144B; Rnf144b
Gene Symbols RNF144B
Host Species Rabbit
Immunogen A synthesized peptide derived from human RNF144B(Accession Q7Z419), corresponding to amino acid residues H83-A133.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 218215, 255488
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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