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RNF144B Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501987870
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100 μL
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50-198-7870 100 μL
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Catalog No. 50-198-7870 Supplier Bioss Supplier No. BS7613R
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Description

Rabbit Polyclonal Antibody

E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a p53/TP53-dependent but caspase-independent mechanism. However, its overexpression also produces a decrease of the ubiquitin-dependent stability of BAX, a pro-apoptotic protein, ultimately leading to protection of cell death; But, it is not an anti-apoptotic protein per se.

Specifications

Antigen RNF144B
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene RNF144B
Gene Accession No. Q7Z419
Gene Alias bA528A10.3; BC025007; E130105P19Rik; E3 ubiquitin-protein ligase RNF144B; IBR domain containing 2; IBR domain-containing protein 2; Ibrdc2; p53-inducible RING finger protein; P53RFP; Pir2; RING finger protein 144B; Rnf144b
Gene Symbols RNF144B
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human IBRDC2/RING finger protein 144B.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 255488
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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