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RNF157 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501988922
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100 μL
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50-198-8922 100 μL
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Catalog No. 50-198-8922 Supplier Bioss Supplier No. BS9226R
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Rabbit Polyclonal Antibody

E3 ubiquitin ligase that ubiquitinates APBB1 for its degradation by the proteasome and thus prevents apoptosis and promotes survival of neurons. Has a dual role in neurons as it is also required for dendrite growth and maintenance for which its ligase activity is not critical. May act as a scaffold molecule to regulate this process. Acts as a downstream effector of the interconnected PI3K and MAPK signaling pathways and thus participates in the regulation of the cell cycle.

Specifications

Antigen RNF157
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene RNF157
Gene Accession No. Q96PX1
Gene Alias E3 ubiquitin ligase RNF157; KIAA1917; RING finger protein 157; RING-type E3 ubiquitin transferase RNF157; RNF157
Gene Symbols RNF157
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human RNF157.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 114804
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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