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Invitrogen™ RNF169 Polyclonal Antibody
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Catalog No. PIPA569238
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100 μL
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Catalog No. Quantity
PIPA569238 100 μL
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Catalog No. PIPA569238 Supplier Invitrogen™ Supplier No. PA569238
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Description

Rabbit Polyclonal Antibody

This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%.

Probable E3 ubiquitin-protein ligase that acts as a negative regulator of double-strand breaks (DSBs) repair following DNA damage. Recruited to DSB repair sites by recognizing and binding ubiquitin catalyzed by RNF168 and competes with TP53BP1 and BRCA1 for association with RNF168-modified chromatin, thereby acting as a negative regulator of DSBs repair. E3 ubiquitin-protein ligase activity is not required for regulation of DSBs repair.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RNF169
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene RNF169
Gene Accession No. Q8NCN4
Gene Alias 2900057K09Rik; E3 ubiquitin-protein ligase RNF169; KIAA1991; RING finger protein 169; RING finger protein 169; E3 ubiquitin-protein ligase RNF169; RING-type E3 ubiquitin transferase RNF169; RNF169
Gene Symbols RNF169
Host Species Rabbit
Immunogen synthetic peptide directed towards the N terminal region of human RNF169.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 254225
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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