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RNF169 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501566872
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50-156-6872 10 μL
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Catalog No. 50-156-6872 Supplier Bethyl Laboratories, Inc Supplier No. A304097AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

Probable E3 ubiquitin-protein ligase that acts as a negative regulator of double-strand breaks (DSBs) repair following DNA damage. Recruited to DSB repair sites by recognizing and binding ubiquitin catalyzed by RNF168 and competes with TP53BP1 and BRCA1 for association with RNF168-modified chromatin, thereby acting as a negative regulator of DSBs repair. E3 ubiquitin-protein ligase activity is not required for regulation of DSBs repair.

Specifications

Antigen RNF169
Applications Immunoprecipitation
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene RNF169
Gene Accession No. Q8NCN4
Gene Alias KIAA1991, RING finger protein 169
Gene Symbols RNF169
Host Species Rabbit
Immunogen Between 200 and 250
Purification Method Antigen affinity chromatography
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 254225
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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