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Invitrogen™ RNF17 Polyclonal Antibody
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Catalog No. PIPA558889
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PIPA558889 100 μL
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Catalog No. PIPA558889 Supplier Invitrogen™ Supplier No. PA558889
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Rabbit Polyclonal Antibody

Immunogen sequence: SYEIGYILKD NSQKHIEVWD PSPEEIISNE VHNLNPVSAK SLPNENFQSL YNKELPVHIC NVISPEKIYV QWLLTENLLN SLEEKMIAAY ENSKWEPVK Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 79%.

RNF17 also termed as ring finger protein 17 is a 1623 amino acid protein, which contains 1 ring type zinc finger and 4 tudor domains. RNF17 is specifically expressed in testis. The RING finger motif presents in many ubiquitin E3 ligases. RNF17 interacts with all four members of the Mad family (Mad1, Mxi1, Mad3 and Mad4), which are basic-helix-loop-helix-leucine zipper transcription factors of the Myc oncoprotein network. RNF17 is component of the tectonic-like complex, which is required for ciliogenesis and sonic hedgehog/SHH signaling. RNF17 is able to form dimers or polymers both in vitro and in vivo, indicating that it may play a role in the assembly of RNF17 granules. RNF17 encodes a novel key regulator of spermiogenesis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RNF17
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene RNF17
Gene Accession No. Q9BXT8
Gene Alias Mad member-interacting protein 2; Max dimerization protein member-interacting protein 2; Mmip2; Mmip-2; RING finger protein 17; Rnf17; SPATA23; spermatogenesis associated 23; TDRD4; tudor domain containing 4; tudor domain-containing protein 4
Gene Symbols RNF17
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human RNF17. Recombinant protein control fragment (Product #RP-97953).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56163
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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