Invitrogen™ RNF17 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5110307

Catalog No. PIPA5110307

Description

Immunogen sequence: VSAKSLPNEN FQSLYNKELP VHICNVISPE KIYVQWLLTE NLLNSLEEKM IAAYENSKWE PVKWENDMHC AVKIQDKNQW RRGQIIRMVT DTLVEVLLYD VGVELVVNVD CLRKLEENLK TMGRLSLECS LVDIRPAGGS DKWTATACDC LSLYLTGAVA TIILQVDSEE NNTTWPLPVK IFCRDEKGER VDVSKYLIKK GLALRERRIN NLDNSHSLSE KSLEVPLEQE DSVVTNCIKT NFDPDKKTAD IISEQKVSEF QEKILEPRTT RGYKPPAIPN MNVFEATVSC VGDDGTIFVV P.

RNF17 also termed as ring finger protein 17 is a 1623 amino acid protein, which contains 1 ring type zinc finger and 4 tudor domains. RNF17 is specifically expressed in testis. The RING finger motif presents in many ubiquitin E3 ligases. RNF17 interacts with all four members of the Mad family (Mad1, Mxi1, Mad3 and Mad4), which are basic-helix-loop-helix-leucine zipper transcription factors of the Myc oncoprotein network. RNF17 is component of the tectonic-like complex, which is required for ciliogenesis and sonic hedgehog/SHH signaling. RNF17 is able to form dimers or polymers both in vitro and in vivo, indicating that it may play a role in the assembly of RNF17 granules. RNF17 encodes a novel key regulator of spermiogenesis.

Specifications

• Antigen: RNF17
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RNF17
• Gene Alias: Mad member-interacting protein 2; Max dimerization protein member-interacting protein 2; Mmip2; Mmip-2; RING finger protein 17; Rnf17; SPATA23; spermatogenesis associated 23; TDRD4; tudor domain containing 4; tudor domain-containing protein 4
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 56163
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 2.82 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q9BXT8
• Gene Symbols: RNF17
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 900-1200 of human RNF17 (NP_112567.2).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG