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Invitrogen™ RNF182 Polyclonal Antibody
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Catalog No. PIPA552925
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100 μL
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Catalog No. Quantity
PIPA552925 100 μL
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Catalog No. PIPA552925 Supplier Invitrogen™ Supplier No. PA552925
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: VLECCHRVCA KCLYKIIDFG DSPQGVIVCP FCRFETCLPD DEVSSLPDDN NILVNLTCGG KGKKCLPENP TELLLTPKRL ASLVSPSHTS SNCLVITIME VQRESSPSLS STPVVEFYRP ASFDSVTTVS HNWTVWNCTS LL Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 99%.

E3 ubiquitin-protein ligase that mediates the ubiquitination of ATP6V0C and targets it to degradation via the ubiquitin-proteasome pathway (PubMed:18298843). Plays also a role in the inhibition of TLR-triggered innate immune response by mediating 'Lys'-48-linked ubiquitination and subsequent degradation of NF-kappa-B component RELA (PubMed:31432514). [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen RNF182
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene RNF182
Gene Accession No. Q8N6D2
Gene Alias E3 ubiquitin-protein ligase RNF182; ring finger protein 182; RING-type E3 ubiquitin transferase RNF182; RNF182
Gene Symbols RNF182
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human RNF182. Recombinant protein control fragment (Product #RP-88711).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 221687
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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