Invitrogen™ RNF19A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA554861

Catalog No. PIPA554861

Description

Immunogen sequence: EMCTDKNSIF STNTSSDNGL TSISKQIGDF IECPLCLLRH SKDRFPDIMT CHHRSCVDCL Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 93%.

This gene encodes a member of the ring between ring fingers (RBR) protein family, and the encoded protein contains two RING-finger motifs and an in between RING fingers motif. This protein is an E3 ubiquitin ligase that is localized to Lewy bodies, and ubiquitylates synphilin-1, which is an interacting protein of alpha synuclein in neurons. The encoded protein may be involved in amyotrophic lateral sclerosis and Parkinson's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013].

Specifications

• Antigen: RNF19A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RNF19A
• Gene Alias: AA032313; Dorfin; Double ring-finger protein; E3 ubiquitin-protein ligase RNF19A; Gametogenesis-expressed protein GEG-154; Geg-154; p38; protein p38 interacting with transcription factor Sp1; ring finger protein (C3HC4 type) 19; ring finger protein 19; ring finger protein 19A; ring finger protein 19A, E3 ubiquitin protein ligase; ring finger protein 19A, RBR E3 ubiquitin protein ligase; ring-IBR-ring domain containing protein Dorfin; Rnf19; RNF19A; Ubce7ip2; UBCM4-interacting protein 117; ubiquitin conjugating enzyme 7 interacting protein 2; UIP117; XY body protein; XYbp
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 25897
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.20 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9NV58
• Gene Symbols: RNF19A
• Immunogen: Recombinant protein corresponding to Human RNF19A. Recombinant protein control fragment (Product #RP-93729).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG