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Invitrogen™ RNF20 Polyclonal Antibody
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Catalog No. PIPA534552
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100 μg
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Catalog No. Quantity
PIPA534552 100 μg
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Catalog No. PIPA534552 Supplier Invitrogen™ Supplier No. PA534552
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Description

Rabbit Polyclonal Antibody

A suggested positive control is human liver tissue lysate. PA5-34552 can be used with blocking peptide PEP-1595.

RNF20 is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. RNF20 selectively suppresses the expression of some genes such as several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor by interfering with chromatin recruitment of transcription elongation factor SII (TFIIS). In contrast, RNF20 also positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. Together with the deubiquitinase USP44, RNF20 regulates stem cell differentiation by modulating H2B monoubiquitination.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RNF20
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene RNF20
Gene Accession No. Q5DTM8, Q5VTR2
Gene Alias 4833430L21Rik; AW540162; BRE1; BRE1 E3 ubiquitin ligase homolog; BRE1A; BRE1-A; C79397; E3 ubiquitin-protein ligase BRE1A; FLJ11189; FLJ20382; hBRE1; HNF3B; homolog of S. cerevisiae BRE1; hypothetical protein; KIAA2779; Kiaa4116; MGC129667; MGC129668; mKIAA4116; RCJMB04_5a23; RING finger protein 20; ring finger protein 20, E3 ubiquitin protein ligase; RING-type E3 ubiquitin transferase BRE1A; Rnf20; TCF3B
Gene Symbols RNF20
Host Species Rabbit
Immunogen A 19 amino acid peptide near the amino terminus of human RNF20.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 109331, 56254
Target Species Human, Mouse
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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