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Invitrogen™ RNF20 Recombinant Rabbit Monoclonal Antibody (SP00-47)
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Catalog No. PIMA542421
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100 μL
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Catalog No. Quantity
PIMA542421 100 μL
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Catalog No. PIMA542421 Supplier Invitrogen™ Supplier No. MA542421
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Description

Rabbit Recombinant Monoclonal Antibody

Positive Control: Jurkat, MCF-7, Hela. Subcellular Location: Nucleus.

RNF20 is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. RNF20 selectively suppresses the expression of some genes such as several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor by interfering with chromatin recruitment of transcription elongation factor SII (TFIIS). In contrast, RNF20 also positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. Together with the deubiquitinase USP44, RNF20 regulates stem cell differentiation by modulating H2B monoubiquitination.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RNF20
Applications Flow Cytometry, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone SP00-47
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene RNF20
Gene Accession No. Q5DTM8, Q5VTR2
Gene Alias 4833430L21Rik; AW540162; BRE1; BRE1 E3 ubiquitin ligase homolog; BRE1A; BRE1-A; C79397; E3 ubiquitin-protein ligase BRE1A; FLJ11189; FLJ20382; hBRE1; HNF3B; homolog of S. cerevisiae BRE1; hypothetical protein; KIAA2779; Kiaa4116; MGC129667; MGC129668; mKIAA4116; RCJMB04_5a23; RING finger protein 20; ring finger protein 20, E3 ubiquitin protein ligase; RING-type E3 ubiquitin transferase BRE1A; Rnf20; TCF3B
Gene Symbols RNF20
Host Species Rabbit
Immunogen Recombinant protein within human rnf20 aa 480-585.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 109331, 56254
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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