Invitrogen™ RNF213 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA555418

Catalog No. PIPA555418

Description

Immunogen sequence: KDPVCLPCDH VHCLRCLRAW FASEQMICPY CLTALPDEFS PAVSQAHREA IEKHARFRQM CNSFFVDLVS TICFKDNAPP EKEVIESLLS LLFVQKGRLR DAAQRHCEHT KSLSPFNDVV DKTPVIRSVI LKLLLKYS Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 79%.

RNF213 is an E3 ubiquitin-protein ligase involved in angiogenesis. Involved in the non-canonical Wnt signaling pathway in vascular development: acts by mediating ubiquitination and degradation of FLNA and NFATC2 downstream of RSPO3, leading to inhibit the non-canonical Wnt signaling pathway and promoting vessel regression. Also has ATPase activity.

Specifications

• Antigen: RNF213
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RNF213
• Gene Alias: 6030403J01; ALK lymphoma oligomerization partner on chromosome 17; ALO17; C17orf27; D11Ertd759e; E3 ubiquitin-protein ligase RNF213; KIAA1554; KIAA1618; mKIAA1554; MYMY2; Mysterin; MYSTR; NET57; protein ALO17; RGD1308168; RING finger protein 213; RING-type E3 ubiquitin transferase RNF213; RNF213
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 57674
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q63HN8
• Gene Symbols: RNF213
• Immunogen: Recombinant protein corresponding to Human RNF213. Recombinant protein control fragment (Product #RP-89516).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov