Invitrogen™ RNF220 Monoclonal Antibody (5E5)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA524470

Catalog No. PIMA524470

Description

Peptide Sequence: QEAMQKTCKN SDIEKITEDS AVTTFEALKA RVRELERQLS RGDRYKCLIC MDSYSMPLTS IQCWHVHCEE CWLRTLGAKK LCPQCNTITA PGDLRRIYL.

E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of SIN3B. Independently of its E3 ligase activity, acts as a CTNNB1 stabilizer through USP7-mediated deubiquitination of CTNNB1 promoting Wnt signaling (PubMed:25266658).

Specifications

• Antigen: RNF220
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: RNF220
• Gene Alias: 4732477A13; 4931406I20Rik; 5730503K05Rik; AV302541; C1orf164; E3 ubiquitin-protein ligase RNF220; ring finger protein 220; RING-type E3 ubiquitin transferase Rnf220; RNF220
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 55182
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunocytochemistry
• Clone: 5E5
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: Q5VTB9
• Gene Symbols: RNF220
• Immunogen: FLJ10597 (NP_060620, 468 a.a. ~ 566 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1 κ