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Invitrogen™ RNF3 Polyclonal Antibody
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Catalog No. PIPA540882
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100 μL
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PIPA540882 100 μL
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Catalog No. PIPA540882 Supplier Invitrogen™ Supplier No. PA540882
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Description

Rabbit Polyclonal Antibody

Peptide sequence: EVPGDIKGET CSAKQHLDSH RNGETKADDS SNKEAAEEKP EEDNDYHRSD Sequence homology: Cow: 86%; Dog: 93%; Guinea Pig: 79%; Horse: 79%; Human: 100%; Mouse: 86%; Pig: 86%; Rabbit: 85%; Rat: 86%; Yeast: 75%.

Phosphorylase kinase is a hexadecameric enzyme that is comprised of four copies of four subunits that are encoded by four separate genes: PHKA, PHKB, PHKG, and PH kDa. This serine/threonine specific kinase converts glycogen phosphorylase b to glycogen phosphorylase a, resulting in the release of glucose-1-phophate from glycogen. PHKB (Phosphorylase b kinase regulatory subunit beta) is a 1093 amino acid subunit of phosphorylase kinase that, along with PHKA, has regulatory functions controlled by phosphorylation. Defects in the gene encoding PHKB are the cause of glycogen storage disease type 9B, which is also known as phosphorylase kinase deficiency of liver and muscle. This disease is characterized by a mild phenotype of hepatomegaly with only slightly elevated transaminase and plasma lipids, no clinical muscle involvement, and generally is correlated with a gradual improvement with increasing age. There are four isoforms of PHKB that are produced as a result of alternative splicing events.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RNF3
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene PCGF3
Gene Accession No. Q3KNV8
Gene Alias 2310035N15Rik; AI662857; D630042K08Rik; D6S113E; DADB-17J1.3; DKFZp686D20235; DKFZp686N0336; DONG1; E430039C14; FLJ31942; FLJ36550; FLJ43813; FSH; FSRG1; KIAA9001; MGC129075 protein; MGC129615; MGC40413; NAT; PCGF3; polycomb group ring finger 3; polycomb group RING finger protein 3; ring finger protein 3; RING finger protein 3A; RING3; RNF3; RNF3A
Gene Symbols PCGF3
Host Species Rabbit
Immunogen Synthetic peptide directed towards the middle region of human PCGF3.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10336
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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