Invitrogen™ RNF4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA561941

Catalog No. PIPA561941

Description

Immunogen sequence: HNDSVVIVDE RRRPRRNARR LPQDHADSCV VSSDDEELSR DRDVYVTTHT PRNARDEGAT Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 85%.

The protein encoded by this gene contains a RING finger motif and acts as a transcription regulator. This protein has been shown to interact with, and inhibit the activity of, TRPS1, a transcription suppressor of GATA-mediated transcription. Transcription repressor ZNF278/PATZ is found to interact with this protein, and thus reduce the enhancement of androgen receptor-dependent transcription mediated by this protein. Studies of the mouse and rat counterparts suggested a role of this protein in spermatogenesis. A pseudogene of this gene is found on chromosome 1.

Specifications

• Antigen: RNF4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RNF4
• Gene Alias: AU018689; E3 ubiquitin ligase RNF4; E3 ubiquitin-protein ligase RNF4; Gtrgeo8; Protein SNURF; RES4-26; RING finger protein 4; RING-type E3 ubiquitin transferase RNF4; RNF4; SLX5; small nuclear RING finger protein; SNURF
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6047
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P78317
• Gene Symbols: RNF4
• Immunogen: Recombinant protein corresponding to Human RNF4. Recombinant protein control fragment (Product #RP-101110).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG