Invitrogen™ RNF40 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA530332

Catalog No. PIPA530332

Description

Recommended positive controls: IMR32, HeLa, HeLa NE. Predicted reactivity: Mouse (86%), Rat (86%), Rhesus Monkey (96%), Bovine (94%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery.

Specifications

• Antigen: RNF40
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RNF40
• Gene Alias: 95 kDa retinoblastoma protein binding protein; 95 kDa retinoblastoma-associated protein; AI848422; BRE1 E3 ubiquitin ligase homolog B; Bre1b; BRE1-B; DKFZp686K191; E3 ubiquitin-protein ligase BRE1B; KIAA0661; MGC13051; mKIAA0661; protein staring; Rb-associated protein; RBP95; RING finger protein 40; ring finger protein 40, E3 ubiquitin protein ligase; RING-type E3 ubiquitin transferase BRE1B; Rnf40; STARING; staring protein; syntaxin-1-interacting RING finger protein
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9810
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O75150
• Gene Symbols: RNF40
• Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human RNF40. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov