RNF41 Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-8920	100 μL

Catalog No. 50-198-8920 Supplier Bioss Supplier No. BS9224R

Description

Rabbit Polyclonal Antibody

The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. Nrdp1, also known as RNF41 (RING finger protein 41), SBBI03 or FLRF, is a 317 amino acid protein that contains one RING-type zinc finger and one SIAH-type zinc finger. Expressed in testis, ovary and prostate, Nrdp1 functions as an E3 ubiquitin-protein ligase that, characteristic of E3 ligase proteins, accepts ubiquitin (in the form of a thioester) from an E2 ubiquitin-conjugating enzyme and transfers that ubiquitin residue to substrates targeted for degradation. Specifically, Nrdp1 interacts with ErbB-3 and UBPY, thereby targeting them for proteasomal degradation.

Specifications

• Antigen: RNF41
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: RNF41
• Gene Accession No.: Q9H4P4
• Gene Alias: 2210404G21Rik; 4930511A05Rik; 4933415P08Rik; D10Ertd722e; E3 ubiquitin-protein ligase NRDP1; fetal liver ring finger; FLRF; neuregulin receptor degradation protein-1; NRDP1; RING finger protein 41; ring finger protein 41, E3 ubiquitin protein ligase; RING-type E3 ubiquitin transferase NRDP1; RNF41; SBBI03
• Gene Symbols: RNF41
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human RNF41.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 10193
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG