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Invitrogen™ RNF43 Polyclonal Antibody
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Catalog No. PIPA552512
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100 μL
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Catalog No. Quantity
PIPA552512 100 μL
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Catalog No. PIPA552512 Supplier Invitrogen™ Supplier No. PA552512
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: CVDPWLHQHR TCPLCMFNIT EGDSFSQSLG PSRSYQEPGR RLHLIRQHPG HAHYHLPAAY LLGPSRSAVA RPPRPGPFLP SQEPGMGPRH HRFPRAAHPR APGEQQRLAG AQHPYAQGWG LSHLQSTSQH Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 79%.

E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components Frizzled. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RNF43
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene RNF43
Gene Accession No. Q68DV7
Gene Alias 4732452J19Rik; E3 ubiquitin-protein ligase RNF43; RGD1305204; RING finger protein 43; RING-type E3 ubiquitin transferase RNF43; RNF124; Rnf43; URCC
Gene Symbols RNF43
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human RNF43. Recombinant protein control fragment (Product #RP-89654).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54894
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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