RNF7 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Catalog No.	Quantity
50-172-7549	150 μL

Catalog No. 50-172-7549 Supplier Proteintech Group Inc Supplier No. 119051AP150UL

Description

Rabbit Polyclonal Antibody

The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Specifications

• Antigen: RNF7
• Applications: Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
• Classification: Polyclonal
• Concentration: 0.13 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: RNF7
• Gene Accession No.: Q9UBF6, Q9WTZ1
• Gene Alias: CKBBP1, CKII beta binding protein 1, Rbx2, Regulator of cullins 2, RING box protein 2, ring finger protein 7, RNF7, ROC2, SAG
• Gene Symbols: RNF7
• Host Species: Rabbit
• Immunogen: RNF7 Fusion Protein Ag2553
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 19823, 300948, 9616
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG