Invitrogen™ RNPS1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA535967

Catalog No. PIPA535967

Description

Recommended positive controls: 293T, A431, HeLa, HepG2. Predicted reactivity: Mouse (100%), Rat (98%), Chimpanzee (98%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. This protein contains many serine residues. Two splice variants have been found for this gene; both variants encode the same protein.

Specifications

• Antigen: RNPS1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RNPS1
• Gene Alias: E5.1; LDC2; ribonucleic acid binding protein S1; RNA binding protein S1; RNA binding protein S1, serine-rich domain; RNA binding protein with serine rich domain 1; RNA binding protein with serine-rich domain; RNA-binding protein S1, serine-rich domain; RNA-binding protein with serine-rich domain 1; Rnps1; SR protein; SR-related protein LDC2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10921
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: Q15287
• Gene Symbols: RNPS1
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 94 of RNPS1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG