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Ro 15-4513, Tocris Bioscience™
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Catalog No. 199750
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Benzodiazepine partial inverse agonist

High affinity benzodiazepine ligand. Ki values are 3.1 and 5.3 nM for diazepam-insensitive (DI) and diazepam-sensitive (DS) benzodiazepine receptors respectively. Acts as partial inverse agonist at recombinant DS α1-, α2-, α3- and α5-GABAA receptors. Displays partial agonism at DI α4- and α6-GABAA receptors. Antagonizes several behavioral and neurochemical effects of ethanol. Proconvulsant and anxiogenic.

Chemical Identifiers

CAS 91917-65-6
Molecular Formula C15H14N6O3
Molecular Weight (g/mol) 326.316
InChI Key CFSOJZTUTOQNIA-UHFFFAOYSA-N
Synonym unii-s5xgl82o5y, s5xgl82o5y, ethyl-8-azido-5,6-dihydro-5-methyl-6-oxo-4h-imidazo-1,4-benzodiazepine-3-carboxylate, ethyl 8-azido-5-methyl-6-oxo-4h-imidazo 1,5-a 1,4 benzodiazepine-3-carboxylate, ethyl 8-azido-6-dihydro-5-methyl-6-oxo-4h-imidazo 1,5-a 1,4 benzodiazepine-3-carboxylate, 4h-imidazo 1,5-a 1,4 benzodiazepine-3-carboxylic acid, 8-azido-5,6-dihydro-5-methyl-6-oxo-, ethyl ester, ethyl 12-azido-8-methyl-9-oxo-2,4,8-triazatricyclo 8.4.0.0^ 2,6 tetradeca-1 10 ,3,5,11,13-pentaene-5-carboxylate, d04ovj, d0m4cp, chembl6597
PubChem CID 5081
IUPAC Name ethyl 8-azido-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate
SMILES CCOC(=O)C1=C2CN(C(=O)C3=C(N2C=N1)C=CC(=C3)N=[N+]=[N-])C

Specifications

Quantity 50 mg
Formula Weight 326.31
Percent Purity >98%
Chemical Name or Material Ro 15-4513

Safety and Handling

Recommended Storage Desiccate at +4°C
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