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  5. Tocris Bioscience™ RO 5263397 hydrochloride

Tocris Bioscience™ RO 5263397 hydrochloride
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Catalog No. 683325
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5 mg
25 mg
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Catalog No. Quantity
68-332-5 25 mg
68-335 5 mg
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Catalog No. 68-332-5 Supplier Tocris Bioscience™ Supplier No. 6833/25
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Description

Potent TA1 receptor agonist

RO 5263397 hydrochloride is a potent trace amine 1 (TA1) receptor agonist (EC50 values are 0.12, 35 and 17-85 nM for mouse, rat and human receptors, respectively). Increases wakefulness and reduces REM and NREM sleep duration in wild type mice. Inhibits spontaneous locomotor activity in dopamine transport (DAT) knockout mice.

Specifications

Chemical Name or Material (4S)-4-(3-Fluoro-2-methylphenyl)-4,5-dihydro-2-oxazolamine hydrochloride
Quantity 25 mg
Target Trace Amine 1 (TA1) Receptor Agonists
Molecular Formula C10H11FN2O.HCl
Formula Weight 3131
Purity 98%
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