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Invitrogen™ ROCK2 Monoclonal Antibody (GT11712)
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Catalog No. PIMA527805
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100 μL
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Catalog No. Quantity
PIMA527805 100 μL
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Catalog No. PIMA527805 Supplier Invitrogen™ Supplier No. MA527805
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Description

Mouse Monoclonal Antibody

Positive Control: 293T, A431, HeLa, HepG2, A549 Predicted Reactivity: Xenopus laevis (80%), Rhesus Monkey (100%), Bovine (97%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

ROCK2, the predominant ROCK isoform in skeletal muscle, is an important regulator downstream of Rho GTPases. ROCK2 regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ROCK2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone GT11712
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7
Gene ROCK2
Gene Accession No. O75116, P70336, Q62868
Gene Alias B230113H15Rik; KIAA0619; mKIAA0619; p150 ROK-alpha; p164 ROCK-2; Rho associated coiled-coil containing protein kinase 2; Rho kinase 2; RhoA - binding serine/threosine kinase alpha (ROK - alpha); rhoA-binding kinase 2; Rho-associated coiled-coil containing protein kinase 2; Rho-associated coiled-coil forming kinage 2; Rho-associated coiled-coil forming kinase 2; rho-associated protein kinase 2; Rho-associated, coiled-coil-containing protein kinase 2; rho-associated, coiled-coil-containing protein kinase II; Rho-kinase; ROCK II; Rock2; Rock2m; rockii; ROCK-II; ROK; ROKalpha
Gene Symbols ROCK2
Host Species Mouse
Immunogen Recombinant protein encompassing a sequence within the center region of human ROCK2. The exact sequence is proprietary.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19878, 25537, 9475
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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