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RORγt Mouse anti-Mouse, RB545, Clone: Q31-378, BD Horizon™

Catalog No. BDB569283 Shop All BD Biosciences Products
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BDB569283 25 μg
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Catalog No. BDB569283 Supplier BD Biosciences Supplier No. 569283
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Description

Mouse Monoclonal Antibody

The Q31-378 monoclonal antibody recognizes mouse RORgamma t (RORγt), an isoform of RORgamma (RORγ). RORγt is a DNA-binding transcription factor that belongs to the ROR/RZR orphan nuclear receptor family. RORγt is expressed exclusively by lymphoid cells including CD4+CD8+ thymocytes, peripheral CD4+ Th17 and CD8+ Tc17 cells, NKT cells and innate lymphoid cells such as lymphoid tissue inducer (LTi) cells. RORγt plays essential roles in thymopoiesis, T cell homeostasis, differentiation of effector T lymphocytes and the development of secondary lymphoid tissues including lymph nodes and Peyer's patches.

RORγt Monoclonal antibody specifically detects RORγt in Mouse samples. It is validated for Intracellular Staining (Flow Cytometry)
TRUSTED_SUSTAINABILITY

Specifications

Antigen RORγt
Applications Flow Cytometry
Classification Monoclonal
Clone Q31-378
Concentration 0.2 mg/mL
Conjugate RB545
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Gene Alias RORγT; RORgt; RORgamma t; RORgammaT; Rorc2; Rorg; TOR; Thor; Nr1f3
Host Species Mouse
Immunogen Mouse RORγt Recombinant Protein
Purification Method Affinity Purified
Quantity 25 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19885
Target Species Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to the dye under optimum conditions and unreacted dye was removed.
Form Purified
Isotype IgG2a κ
Excitation/Emission Excitation Source: Blue 488 nm, Excitation Max: 496 nm, Emission Max: 545 nm
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