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ROR1 Mouse, anti-Human, R718, Clone: 4A5, BD OptiBuild™

Catalog No. BDB751907 Shop All BD Biosciences Products
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BDB751907 50 μg
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Catalog No. BDB751907 Supplier BD Biosciences Supplier No. 751907
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Description

Mouse Monoclonal Antibody

The 4A5 monoclonal antibody binds to the glycosylated type I membrane protein ROR1 (Receptor-tyrosine-kinase-like Orphan Receptor 1). The ROR1 and ROR2 related proteins are highly conserved evolutionarily and are primarily expressed during embryogenesis. ROR1 is not expressed on normal peripheral blood lymphocytes. ROR1 is similar to tropomyosin receptor kinase (Trk family) neurotropic receptors and shares a cysteine-rich domain with Frizzled receptors for Wnt-family signaling proteins, which are involved in the regulation of embryogenesis and carcinogenesis. Furthermore, there is mounting evidence that aberrant ROR1 expression contributes to human malignancy.

TRUSTED_SUSTAINABILITY

Specifications

Antigen ROR1
Applications Flow Cytometry
Classification Monoclonal
Clone 4A5
Conjugate R718
Host Species Mouse
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Refrigerate Upon Arrival
Form Liquid
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