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Description
The protein encoded by this gene is a receptor protein tyrosine kinase and type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors. The protein may be involved in the early formation of the chondrocytes and may be required for cartilage and growth plate development. Mutations in this gene can cause brachydactyly type B, a skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In addition, mutations in this gene can cause the autosomal recessive form of Robinow syndrome, which is characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly, and a dysmorphic facial appearance. [provided by RefSeq]
Specifications
Specifications
| Antigen | ROR2 |
| Applications | ELISA, Flow Cytometry, Western Blot |
| Classification | Monoclonal |
| Clone | 6F2D10 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against partial recombinant human ROR2. |
| Dilution | ELISA (1:10000) Flow Cytometry (1:200-1:400) Western Blot (1:500-1:2000) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS (0.05% sodium azide) |
| Gene Alias | BDB/BDB1/MGC163394/NTRKR2 |
| Gene Symbols | ROR2 |
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