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RORB Monoclonal Antibody (OTI4B7), TrueMAB™, OriGene
SDP

Catalog No. 501681324
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100 μL
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Catalog No. Quantity
50-168-1324 100 μL
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Catalog No. 50-168-1324 Supplier OriGene Supplier No. TA806944
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Description

Mouse Monoclonal Antibody

Retinoid-related orphan receptor beta (ROR beta), a NR1 thyroid hormone receptor, affects the development and functioning of the central nervous system, including sensory input integration and circadian timing. Disruption of ROR beta in mice results in juvenile ataxia, retinal degeneration, circadian activity abnormalities, and delayed onset of male fertility. ROR beta binds to the monomeric response elements containing the sequence AnnTAGGTCA as a monomer. An alternatively spliced isoform, ROR beta2, has been isolated from rats, and the expression of ROR beta2 is confined to the pineal gland and retina. ROR beta2 shares common DNA- and putative ligand-binding domains with wild-type ROR beta but is characterized by a different amino-terminal domain. ROR beta expression has been documented in various regions of the mouse brain.

Specifications

Antigen RORB
Applications Western Blot
Classification Monoclonal
Clone OTI4B7
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene RORB
Gene Accession No. Q92753
Gene Alias NR1F2, ROR-BETA, RZR-BETA, RZRB, bA133M9.1
Gene Symbols RORB
Host Species Mouse
Immunogen Human recombit protein fragment corresponding to amino acids 1-260 of human RORB produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6096
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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