RORB Mouse anti-Human, Clone: OTI1C11, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF806945

Catalog No. 50-166-8047

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Retinoid-related orphan receptor beta (ROR beta), a NR1 thyroid hormone receptor, affects the development and functioning of the central nervous system, including sensory input integration and circadian timing. Disruption of ROR beta in mice results in juvenile ataxia, retinal degeneration, circadian activity abnormalities, and delayed onset of male fertility. ROR beta binds to the monomeric response elements containing the sequence AnnTAGGTCA as a monomer. An alternatively spliced isoform, ROR beta2, has been isolated from rats, and the expression of ROR beta2 is confined to the pineal gland and retina. ROR beta2 shares common DNA- and putative ligand-binding domains with wild-type ROR beta but is characterized by a different amino-terminal domain. ROR beta expression has been documented in various regions of the mouse brain.

Specifications

• Antigen: RORB
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: RORB
• Gene Alias: NR1F2, ROR-BETA, RZR-BETA, RZRB, bA133M9.1
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6096
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Western Blot
• Clone: OTI1C11
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: Q92753
• Gene Symbols: RORB
• Immunogen: Human recombit protein fragment corresponding to amino acids 1-260 of human RORB produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b