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  5. Tocris Bioscience™ Rosiglitazone

Tocris Bioscience™ Rosiglitazone
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Catalog No. 532550
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53-255-0 50 mg
53-251-0 10 mg
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Catalog No. 53-255-0 Supplier Tocris Bioscience™ Supplier No. 5325/50
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Description

Potent and selective PPARγ agonist; antidiabetic agent

Rosiglitazone is a potent and selective PPARγ agonist (EC50 = 60 nM); exhibits no activity at PPARα and PPARβ. Promotes differentiation of pluripotent C3H10T1/2 stem cells into adipocytes. Also promotes differentiation of urothelial organoids in combination with Erlotinib (Cat. No. 7194). Exhibits antihyperglycemic activity in diabetic ob/ob mouse model. Antidiabetic agent.

Specifications

Chemical Name or Material 5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione
CAS 122320-73-4
Synonym BRL 49653
Quantity 50 mg
Target PPAR gamma Receptor Agonists
Molecular Formula C18H19N3O3S
Formula Weight 357.43
Purity 98%
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