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Invitrogen™ RPA4 Polyclonal Antibody
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Catalog No. PIPA544243
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100 μL
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PIPA544243 100 μL
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Catalog No. PIPA544243 Supplier Invitrogen™ Supplier No. PA544243
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Description

Rabbit Polyclonal Antibody

Peptide sequence: VPVSPSEVND AGDNDESHRN FIQDEVLRLI HECPHQEGKS IHELRAQLCD Sequence homology: Human: 100%.

The single-stranded-DNA-binding proteins (SSBs) are essential for DNA function in prokaryotic and eukaryotic cells, mitochondria, phages and viruses. Replication protein A (RPA), a highly conserved eukaryotic protein, is a heterotrimeric SSB consisting of three subunits that play an important role in DNA replication, recombination and repair. RPA is one of the major damage- recognition structures involved in the early stage of nucleotide excision repair and may function in telomere maintenance. The binding of human RPA (hRPA) to DNA involves molecular polarity, in which initial hRPA binding occurs on the 5' side of a ssDNA substrate and then extends in the 3' direction to create a stably bound hRPA. Widely expressed at low to intermediate levels, RPA 34 kDa subunit, which is also known as RPA4 (replication factor A protein 4), contains 261 amino acids, localizes to nucleus and is preferentially expressed in mucosa of colon and placenta.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RPA4
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene RPA4
Gene Accession No. Q13156
Gene Alias HSU24186; MGC120333; MGC120334; Replication factor A protein 4; replication protein A 30 kDa subunit; replication protein A complex 34 kd subunit homolog Rpa4; replication protein A4; replication protein A4, 30kDa; replication protein A4, 34kDa; RF-A protein 4; RP-A p30; RPA4
Gene Symbols RPA4
Host Species Rabbit
Immunogen Synthetic peptide directed towards the middle region of human RPA4.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 29935
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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