Invitrogen™ RPAIN Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA556770

Catalog No. PIPA556770

Description

Immunogen sequence: MAESLRSPRR SLYKLVGSPP WKEAFRQRCL ERMRNSRDRL LNRYRQAGSS GPGNSQNSFL VQEVMEEEWN Highest antigen sequence identity to the following orthologs: Mouse - 71%, Rat - 73%.

Replication protein A (RPA) is a single-stranded-DNA binding protein involved in numerous eukaryotic DNA processes including replication, repair and recombination. RPA interacting protein (RPA IP) has been identified as an adapter protein that is involved in RPA nuclear import instead of the prototypical importin proteins that normally mediate nuclear import. Multiple isoforms of RPA IP are known to exist, with the longest isoform localized to the cytoplasm. Isoform 2 is sumoylated and is located in the PML nuclear body within the nucleus. It has been suggested that this isoform mediates the localization of the RPA complex into the PML nuclear body, thereby participating in RPA function in DNA metabolism.

Specifications

• Antigen: RPAIN
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RPAIN
• Gene Alias: 2400006N03Rik; hRIP; nuclear transporter; RAP interaction protein; RAP interaction protein alpha; RGD1308492; RIP; RPA interacting protein; RPA interacting protein delta 2; RPA interacting protein epsilon; RPAIN; RPA-interacting protein
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 84268
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q86UA6
• Gene Symbols: RPAIN
• Immunogen: Recombinant protein corresponding to Human RPAIN. Recombinant protein control fragment (Product #RP-93237).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov